Healing after breast cancer surgery may trigger relapse

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New research suggests the healing process following breast cancer surgery may be triggering cancer in other parts of the body.

According to MIT News, previous studies of breast cancer patients indicate they are prone to metastatic relapse 12 to 18 months after undergoing surgery for growth removal.

It's been suggested that dormant cancer cells in other sites that were previously kept in check by the immune system are allowed to become active as the body focuses on healing its wound.

Experiments on mice conducted by the Whitehead Institute found that while T-cells stalled the growth of injected cancer cells, simulated surgeries in areas far from the cancer resulted in increased tumor growth and incidence.

Mice given anti-inflammatory drugs during or after surgery developed significantly smaller tumors, which often disappeared completely.

Early research in humans shows the same strong association between anti-inflammatory drug use and a decline in metastasis, but more studies are needed.

RUNDOWN SHOWS:
1. Breast cancer patients prone to relapsing within 12 to 18 months of surgery
2. Cancer cells in other sites allowed to spread during post-surgery wound healing
3. Depiction of experiment on mice
4. Anti-inflammatory drugs given after surgery prevented tumor growth and spread

VOICEOVER (in English):
"Studies of breast cancer patients indicate that they are prone to metastatic relapse 12 to 18 months after surgical growth removal."

"It's believed that dormant cancer cells in other sites previously kept in check by the immune system become active as the body focuses on healing its wound."

"Experiments on mice found that while T-cells stalled the growth of injected cancer cells, simulated surgeries in areas far from the cancer resulted in increased tumor growth and incidence."

"Mice given anti-inflammatory drugs during or after surgery developed significantly smaller tumors, which often disappeared completely."

SOURCES:
MIT News, USA Today
http://news.mit.edu/2018/perioperative-nsaids-may-prevent-early-metastatic-relapse-in-post-surgical-breast-cancer-patients-0411
https://www.usatoday.com/story/news/2018/04/11/breast-cancer-surgery-healing-study/506525002/