Scientists combine cancer drugs to treat melanoma

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Scientists have combined two experimental cancer drugs to treat melanoma.

As part of a study published in the journal Molecular Cancer Therapeutics, researchers paired protein kinase inhibitors and ribonuclease before releasing them onto cancerous tumors.

The protein kinases inhibitors work to bind and block the functions of enzymes that have been affected by cancer cells. This slows the spread of the disease. The ribonuclease then works to enter the tumor and destroy its RNA.

The study found that the drug combination worked more effectively to treat melanoma than individual treatments of each drug.

RUNDOWN SHOWS:
1. Protein kinase inhibitors and ribonuclease, along with cross-section of melanoma
2. The combined drugs being released onto the tumor
3. The protein kinase inhibitors and ribonuclease working together to destroy cancer cells
4. Protein kinase inhibitors and ribonuclease combined working to treat melanoma on the skin

VOICEOVER (in English):
"Scientists have combined protein kinase inhibitors and ribonuclease — two experimental cancer drugs — to treat melanoma."
"As part of a study published in the journal Molecular Cancer Therapeutics, researchers paired both together and released them onto cancerous tumors."
"The protein kinases inhibitors work to bind and block the functions of enzymes that have been affected by cancer cells.
"This slows the spread of the disease."
"The ribonuclease then works to enter the tumor and destroy its RNA."
"The study found that the drug combination worked more effectively to treat melanoma than individual treatments of each drug."
SOURCES:New Atlas, Molecular Cancer Therapeutics, Technology Networks.com, Science Daily, Medical News Today, MIT News,
https://newatlas.com/two-experimental-cancer-drugs-team-up/57504/
http://mct.aacrjournals.org/content/17/12/2622
https://www.technologynetworks.com/cancer-research/news/drug-combo-could-be-more-effective-against-melanoma-312795
https://www.sciencedaily.com/releases/2018/12/181203131130.htm
https://www.medicalnewstoday.com/articles/323884.php
http://news.mit.edu/2018/new-drug-combination-melanoma-1203